Anthony Small headlines Frank Warren's fourth annual DebRA charity dinner on Friday, September 12, at the Grosvenor House Hotel, London.
The three previous events have raised a combined total in excess of £1million, and have been attended by the stars of stage, screen and sport.
In a special UK v s.USA fight card, Small will take on former Contender star Freddie Curiel.
Top heavyweight prospect Derek Chisora will box over eight rounds, while 2006 Commonwealth Games Gold Medallists Jamie Cox and Kenny Anderson fight in six rounders.
The money raised will help promote research into the cause, nature, treatment and cure of the agonising skin genetic disorder Epidermolysis Bullosa (EB) - often referred to by the medical profession as the worst and least publicised condition in the world.
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