Scores were 117-111 and 116-112 for Castillo while one judge saw Casamayor winning by a margin of 115-113.
IBF super middleweight champion Jeff Lacy won a unanimous twelve round decision over multiple time world title challenger Omar Sheika.
Lacy took the decision by margins of 115-113 on two cards and 117-111 on the other.
In the nights heavyweight attraction, Nigeria’s undefeated prospect Samuel Peter exploded onto the heavyweight scene with a devastating second round knockout of Jeremy Williams.