I am not a big Canelo fan, but I don't understand how the Mayweather fight can be used against him. He was young, he stepped in with a very smart, very skilled fighter. He lost and he used the experience to improve himself. That was a decade ago and anybody that cannot see how that fight made him better hasn't been paying attention.
Nobody wins every fight, not if they have balls and take chances. Canelo lost and got better because of it, which is exactly what you are supposed to do.