As long as Cotto uses his underated boxing skills and doesn't trade with Margarito as he did against Corley and Torres, then Cotto should win a lopsided decision. Cotto has the power to keep Margarito honest, but not to stop him from coming forward the entire fight. And Margarito will be the hardest puncher Cotto has faced, as well as the most dedicated body puncher Cotto has faced. Cotto better be in top shape and train for a marathon instead of a track meet.