I've noticed that when Mayweather fights someone whom he feels physically superior to, he tends to go on attack mode as early as possible. Thus, I predict that Mayweather will try to take out Marquez as soon as the bell rings (I am not saying Mayweather will go at Marquez a la Hatton vs. Manny).

However, this approach could be tricky because Marquez is a counterpuncher and this style that Mayweather will use (in my opinion) may leave him open to counters moreso than ever. Still, I don't think Marquez will carry his power to that weight. Most likely a mid late round ko for Mayweather.