Pac hasn't faced a naturally bigger & free swinging non retreating Neanderthal like Margarito. Speed wise its night and day but Margarito brings that natural and current size and range which Manny has not met. I give Clottey size but a hollow chest....Cotto the skill but weight bs and was off two bruising cutting wars . Biggest question is psychological for Margarito off wrap gate and tko to Mosley. He's not new to taking punishment and even being on the floor so I dont think it will phase Tony as much physically. He's always been hit,not news. Mosley was battle tested at weight and bigger then Pac, using Mayorga as a Margarito doppleganger going in. Now has the Pandora's box on his vaunted chin been opened by Shane...remains to be seen. Manny will have to fight one of the most complete fights,in and out as he has to punch in between the volleys. I favor Manny on speed,speed kills and ...but this is not a gimme and he will be hit often like he has not been by a foe not going back wards. Could be brutal as first to back straight will surely have the other atop his chest taking advantage.