Cotto will give a good account of himself, but it's Mayweather's defensive skills that will win him the fight. I just don't see Cotto hitting him enough to take a decision. Mayweather will land plenty and win a wide UD. Cotto will make him work it for it though and Maywether will need all of those defensive skills, i see neither fighter winning by KO. Mayweather by UD 117-111 with Cotto winning a few early rounds. Mayweather is a master of working out his opponent, he comes to the ring with a plan B, he will simply outbox Miguel Cotto.