Castillo and De La Hoya used the jab against Mayweather. Castillo got robbed in their first bout, OScar was going somewhere till he did drop the jab and that his crap endurance got over. Cotto will be bigger and stronger physically, what I'd do is jab Mayweather to death (and Cotto has a very good jab, very good power and is quite fast), pressure him and hit the body with these vicious hooks, especially because his body is always a bit vulnerable in the shoulder roll stance.

I really believe Cotto has his chances in that one and if Manny could bolt his head to death (while he was trained by a nutritionist), I doubt that pillow fisted FLoyd could really hurt him and will have to (if he wins) get the already known UD ticket.