Mosley has trouble with a lot of those guys on that list. He'd easily beat gatti and hatton because they are there to be hit and don't really pose much of a threat to him. I think pryor, while certainly a threat, is too much right there to get hit and Shane could probably beat him. In fact, it wouldn't suprise me to see him get a 3kd tko without ever really hurting Pryor.
My knowledge of Locche is limited, but what I've seen leads me to believe that Mosley would beat him. Locche is veryhard to hit, but he can't keep Mosley off of him, and I don't think that you'll beat Mosley if he isn't a bit afraid of you. That is why I think he'd probably beat Whitaker. Shane is just as fast, and at 135 was real confident and slick. I call him and Benitez at 147 a toss-up. A fight with Cuevas could turn out like the Margarito fight, but if Cuevas gets home early, he'd stop Mosley.
Those other guys are a class above mosley, and when you start talking about guys like Robinson, leonard, Zivic, Gavilan and Basilio, they'd just run Shane out of the ring.
mosley steamrolled guys at 135 because he had a major advantage in physicality and he wasn't afraid to let himself fight and do all that he was capable of doing. At 147 and above, this was not the case and he fought scared. This began in the Rivera fight, and it became really evident in the first DeLaHoya fight. Oscar had the same problem and that is why that fight looked like two old ladies fighting over a clothesline.