The Pacquiao loss removes a Mayweather-Pacquiao fight from the table, unless Pacquiao avenged the Marquez loss with a knockout of Marquez.

Other than Pacquiao, which isn't an option any longer, there are only two fights out there that really mean anything for Mayweather, Canelo and Martinez. One could argue Trout, since he beat Cotto, but that's not a mega-fight the way those other two are.

If you're Pacquiao, its Marquez again and Mayweather if you win.

If you're Marquez, there's Pacquiao again, and if he would meet him at 150, there is Cotto.