I don't now if you can say Tyson, true he never really came back after the loss... at least reached the same heights (he got the WBC after being in Jail after something like 5 rounds of boxing) or notoriety...

But he was never the same after his biggest ($$$) fight with Spinks... he turned into a (bored and distracted) puncher instead of a (motivated) calculated pressure fighter and counter puncher... His mental immaturity and the death of his mentors and protectors and the stupid decision to get rid of Kevin Rooney is what did him in.