I've seen a 110 lbs 15 year old girl in a rage, rip a door off its hinges with one hand and throw is down a flight of stairs. No drugs in her system. She had an autoimmune condition that caused excessive antibodies in her brain. The labs could not detect anything in her system because there was nothing there that was developed in standard test to know what to look for. They only found the antibodies years later because a lab technician developed a test that looked for the antibodies. There is only one lab that can do it.