He defeated Ray Mancini, Roberto Duran (twice), Sugar Ray Leonard, Tony Menefee, Heath Todd, Gary Kirkland, Luis Maysonet, Jorge Vaca, Todd Foster, Pat Lawlor, Reyes Antonio Cruz, Greg Haugen, Tony Baltazar, Ken Sigurani, Howard Davis, Jr, Cornelius Boza Edwards, Freddie Roach, Vinny Paz, Edwin Rosario, Jose Luis Ramirez ( a member of the World Boxing Hall of Fame), Rafael Limon, John Montes, Greg Conversion, Melvin Paul, and Louis Burke. He was defeated by Julio Cesar Chavez, 108-6-2, Felix Trinidad, 42-2, Greg Haugen, 40-10-1(he lost by an extremely controversial decision when, inexplicitly, he was penalized for not touching gloves before the last round; he won the rematch), Oscar De La Hoya, 38-4, and Chris Walsh, 19-7-1 by TD. He didn't fight either Chacon or Pernell Whitaker, but not from his own doing. Bobby Chacon chose to fight Ray Mancini, and the Duvas never made the match with Whitaker.

Era: 1980-2005...multiple eras over a 25 year boxing career. Camacho has been fighting for 25 years. When you consider that Archie Moore's career spanned 27 years, you get a better perspective....though Hector's fight have been far and few between in recent years. Nevertheless, he fought at or near the top of his divisions during eras that included great fighters. The list of his opponents reads like a "whose who" of tough fighters; it includes an astounding fourteen world champions including Hall of Famers, Sugar Ray Leonard and Edwin Rosario, and at least four future inductees (De La Hoya, Duran, Chavez, and Trinidad). And to Camacho's credit, he has never been stopped and has been down arguably only once. In 1989, when he met former world lightweight champion Ray "Boom Boom " Mancini (who was 29-3 with 23 knockouts coming into the fight), Camacho won a unanimous decision for the vacant WBO Junior Welterweight title. In so doing, he joined an exclusive "club" of world champions boxers who have become three-time world champions