IMHO Mosley will beat him decisively. Look at Zab with his awesome speed and how when he worked he gave serious problems to Cotto. Shane is very fast but will take advantage of the angles Cotto will give him. Cotto does use his jab to get close but then looks like the bull going after the matador. Shane will slip out to the side, as Zab did, but unlike Zab will punish Cotto from angles severely. Cotto takes way too long to turn around and I don't see Shane losing that one big advantage. Even if somehow Cotto beats Shane, there is no way that Cotto would beat Mayweather, as that dude would definately make someone suffer from outside angles. I give Hatton more chance against Floyd then I would Cotto, as Cotto is not as quick. Speed kills and it will when Cotto and Mosley get it on.