I don't know the details of this case....
But generally speaking, you don't just pop 1 too many. Things like that can happen, but in that case there would be other complications, like drug-drug interactions. When they do tox studies, they do them on very large doses. So with many drugs, you can take far more than what they say is safe. (I was in drug discovery chemistry for 8+ years). But again, there could have been things to complicate matters in which case, an otherwise safe dose could have proven fatal.
Also, I battled depression for years. A mild case where I was just pissed off a lot. It can be genetic or (and in my case) triggered. My dad died 15 years ago and then stress of school, grad school, job, more grad school, hating my job and not being able to find a new one.... etc. If I wasn't on meds I'd just be pissed off all the time because of life's shitballs. With that said, all the stress and triggers CAN actually lead to low seratonin levels, at which point event-triggered depression can become a chemical imbalance.
This is the kind of shit I did for a living. I actually worked on several seratonin projects.
http://en.wikipedia.org/wiki/Serotonin
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