I believe Cotto has the boxing ability to defeat Margarito in a unanimous decision. The problem for Cotto is that he will be pressured from the opening bell. Margarito will be physically stronger than Cotto. Margarito will be able to maintain his pressure throughout the entire fight. And Margarito can hurt Cotto either to the body or to the head. This will be a fight that Cotto will be STUPID to stand and brawl with Margarito. Cotto will have to stick and move, jab, and flurry all night long, basically staying out of danger for the entire fight. This is one of those fights that Cotto and all of his fans should be happy with a victory no matter how it comes because the styles clash negatively for Cotto. Cotto will not KO or impose physical damage as he has against other opponents. The fact that he won't is a testament to Margarito as opposed to a negative of Cotto's boxing ability. I still say Cotto will be able to hit Margarito cleanly all night long and puff up Margarito's face. He's just so easy to hit, but definitely hard to KO. More than ever, Cotto will have to show once and fo all that he can box with the best of them. I think he will show it if he hasn't already.