I once watched a Cotto fight maybe 2 yrs ago where he was cut over his eye and bleeding pretty steadily. He got cut around Round 6 or 7 and he was on his way to viciously knocking his opponent out. Once he saw his own blood, he became like Ivan Drago being cut in Rocky 4. He suddenly became more tame and afterwards, he told the interviewer, "the blood saved him." Maybe someone else remembers the fight. It was when he first started to learn English. So I do believe that Cotto is/was greatly affected by being bloodied, or cut, or having his nose broken. But I wont take any credit away from Margarito. His relentless approach had as much to do with Cotto's reaction, if not moreso, than Cotto's nose.