I know this isn't pugilistic dementia but I thinks there's some correlation with this thread. Frank Bruno and my dad both suffer from a form of depression called bipolar syndrome, my dad boxed 42 amateur fights over 7 years, and I wonder if there's any link. Bipolar is caused by irregular levels of serotonin and dopamine being released at different times, causing over-happiness followed by crushing 'downers' that last much longer. Any insights?