Kind of a dumb question, but..

[Youngblood]

I honestly have no idea. When in doubt, jab your thumb in his eye.

[Andre]

Depends on the target ,hard targets of bone you want the larger knuckles, also if your fist is thrown vertical or horizontal or on a twist. Occcasionally a vertical fist and bottom three fits in real nice to the body and on a 45% angle into the neck they work well in some combat. You dont want to knock your little finger knuckle backwards if you slightly miss a hard target either, like on a high hook.

[atgatt]

Very interesting about getting more hardness through a glove when punching. Forgive my lack of glove boxing experience. I could only speak of my street fights that punching the body is much easier on the hands than hitting the head area. Knuckles into hard bones hurt. So do teeth.

At least they have better boxing gloves today. When I read about the boxers in the early 1900s, those gloves had padding that broke down during the fight giving some bad hand pain.

[Rocky Balboa]

To align the two knuckles properly you have to cock your fist down and a bit out. Once you get the hang of it your fist will be quite solid.

Youngblood: x2, nothing wrecks his vision more than a thumb in the eye