I don't think you can say that with any degree of certainty. It would be very very close. Pernell was at least as unpenetratable as Mayweather in his prime, and Chavez had an amazing amount of fights, though I think his ducking of many great fighters will affect his legacy...like for example failing to fight pernell again after pernell was robbed.
ODLH ended up losing (albeit very closely) too many big fights and Tito was exposed as a one-trick pony by ODLH himself, so its fair to say both Pac and Mayweather will surpass those two.
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