When I was testing medicine because I was way too poor, I could have sometimes 20 blood draw per day and in all honesty, I went to play sports the monday just after. never felt weak or anything, the blood quantity is way too small, it's not like if they take one litter and half for blood donation, the body can cope with it damn well and if I can survive that, no doubts that a top elite fighter like Manny can survive it all.