I think, Mayweather is the best P4P 'defensive' fighter or this era and Pacquiao is the best P4P 'offensive' fighter of this era. They both have amazing resumes. Pacquiao's status continues to grow beyond that of Mayweather each time he steps into the ring. Mayweather is not exactly doing the same thing to his status.

I've thought Pacquiao would beat Mayweather on points before his fight with Margarito and still think he would do so if they ever the two get into the ring. The shots pacquiao took from Margarito were huge and he weathered them. I can't see Floyd slowing down Pacquiao even with his best pot shot. The thing is, Mayweather plays to the level of his competition. In order to win against Pacquiao, he would have to step up his game to another level. He cannot win against Pacquiao throwing 29 punches a round even, with 70% accuracy, hoping to reduce to Pacquiao's accuracy down lower than 30%.

Can you see Mayweather doing what he did to Mosley against Pacquiao? Mosley had absolutely no gas from the 3rd round on. What Pacquiao did against Margarito, should convince anyone that Mayweather's game plan against Mosley won't be what he uses against Pacquiao. Marquez is a completely different story. So your guess is as good as mine as to what strategy he'll use against Pacquiao. What ever does, it won't be easy.