i use this: 2-1-2 with the second '2' having a hook to it. Shane Mosely uses this type of right hand. Kind of like a cross/overhand hybrid.

here is the important part (at least for me). Your distance has to be a half step closer then it is with a straight right. I advance with the 2-1 to help cover ground, and then the hook it close enough to come around the guard if needed.

Many guys are not used to defending against this angle too. They will bring their guard up, but they wont cover the side of the head/temple/jaw like we are so used to when defending against a left hook.