I think Cotto comes away with the win in this one. Last time i believe he took that fight a little easy when he was applying the pressure he did well and for the first half of the fight he was winning but he didn't have enough in the tank to go the full 12 thus why in the second half of the fight Margarito took charge. This time he will have have taken the fight very seriously and will want to put a serious beating on Margarito. I predict a wide points victory for Cotto and a bad beating beating for Margarito.