Roy Jones Jr.
Willie Pep
Mayweather Jr.
Whitaker
Winky Wright

all had/have great reflexes but that doesn't always mean everything. Ali had great reflexes, but when he fought flat footed he was relatively easy to hit footwork aside. Leonard also appeared that way. Michael Nunn, Meldrick Taylor, Shane Mosley all have great reflexes, but they could be hit. What of the top mentioned guys had the best defensive style in that the most people could use it effectively? I would say Wright.