Cotto by late TKO. Cotto's loses were from extraordinary circumstances, Margarito is a CHEAT and with his fight with PAC he was with a not so good trainer. Too bad the beating he took from the margarito fight alone softened his facial strcuture but otherwise as long as he is healed up he will destroy Mayorga. Cotto is the perfect blend of power and technique, Mayorga will not win.