"De-population" sounds a little cold, Victor. To be sure, in all of the Americas, many indigenous indian cultures were systematically wiped out. But as has been repeated often, this happened over decades and even centuries. It was also the result of warring between colonists from Europe and the indian inhabitants. Indians were not led helplessly in single file into a volcano pit or anything like that. Many colonists lost their lives as well. It was a different time back then. New worlds were still being discovered. This is why I and everyone else disagrees with Miles comparing this to the extermination of the Jews by the Nazis. Europe's colonists and the indian cultures in both Americas were not going to be able to coexist.