Here's a quick break down of the betting odds on a few of Floyd's previous opponents and the odds in the Canelo fight (these are approximate):

Mayweather vs. Marquez - odds were -360 favoring PBF
Mayweather vs. Ortiz - odds were -600 - -800 favoring PBF
Mayweather vs. Guerrero - odds were -750 favoring PBF
Mayweather vs. Cotto - odds were -800 favoring PBF
Mayweather vs. Mosley - odds were -450 favoring PBF


Mayweather vs. Canelo - odds are -200 - -300 favoring PBF