As they say, use it or lose it.. If you have a big enough absence from training, your muscles will eventually start to shrink.
I'm not sure creatine will help keep your muscles. If you can drink enough water, it will keep them hydrated, thereby keeping and optimum environment for them to stay healthy.
L-Glutamine is something you should look into.. It's a little more expensive than creatine, but really helps prevent muscle loss. It is pretty much pumped into burns victims or trauma victims in hospitals where their immune systems are hard at work repairing their body. It helps slow the body eating itself and helps cells rebuild. This will probably be better for your task that creatine.
The absolute main thing though is to make sure your body had enough protein, calories & glucose. Without training, your muscles will eventually decline no matter what you do,,, but without a sufficient intake of nutrients, your body may resort to taking what it needs (energy) from your muscles, and this will surely lead them to decline faster.
If you have a good training routine that you have been sticking to regularly (which it sounds like you have), your body is going to LOVE the 2 weeks off. It will help everything repair to it's maximum. Your metabolism will alter slightly, your muscles will relax and realise it's "Off time", and basically your whole body will relax a little.
This is GREAT news, as when you get back into training, it will be a "shock" to your system, and you could get some great gains!! Most likely if you look at it over a 4 month period, you'll probably make more progress having these 2 weeks off during the 4 months, than if you just worked out straight for the 4 months without a break.
I always felt bad about having time off training, but your body needs time off every now and then, and it only does good for you in the long run..
So RELAX, enjoy your vacation, don't stress about your training to much, and just use the time to get yourself pumped and looking forward to getting back in the gym for some super intense sessions!
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