Margarito getting stopped isn't inconceivable. He was hurt on a few different occasions versus Daniel Santos in their two fights and was bothered by the quick straight punches of Santos. Of course I think he was a bit robbed in both of those fights but he was hurt. Cotto is a great finisher, Margarito will have a tough time seeing his punches, I think rounds 5 or 6 are a bit early but a late stoppage is in no way out of the question imo.