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Think both would get KO'ed, may be able to run for a few rounds but once they get pinned in a corner that will be all she wrote, but as said there will be other heavyweights and other middleweights they may do a little better against but that is a massive disadvantage
Well I agree both would get slaughtered and it wouldnt be close but I think Izzy would probably be decapitated and smashed to pieces, where as Pavlik would probably be able to hang in there a little longer before succumbing to the size disadvantage... Its amazing how that 40lbs effects everything so dramatically...

Just like most including myself would favor a Marciano at 185lbs would beat a Wlad Klitschko at 240lbs despite giving up 55 lbs

But Izzy dosent stand a snowball chance in hell only giving up 40lbs to Pavlik
It's not just weight though, reach is a huge part as well, and the deficit Pavlik has to Wlad is nowhere near what Izzy has to Kelly.
True as like I stated earlier height would have a big difference and the naturally bigger reach...

Thats the thing when you are weighing at 120 lbs your body density heigh weight become a dramatic desparity compared to what you would consider at a higher weight