Guns are a tool. You need different tools for different jobs.

The 'jobs' you are likely to encounter are;

* Walk em up hunting. AND,
*Tree stand or ambush hunting.

3 different game categories; Small, medium and large game, requires 3 different tools. Walking with a rifle all day also requires some consideration to weight of the rifle and its 'handiness', Barrel length.
Small game; Bolt action .17wmr
Medium game; Bolt action 22/250, 243, 7mm08.
Large game; semi-auto, bolt action 270, 30/06 (or larger)

*Varmining

As you are in one position and not walking around, weight is not a major concern, accuracy and range is.
Small game; Bolt action, 17wmr to 22/250 or 220 swift.
Medium game; Bolt action, 243 all the way to the 25/06 and the Weatherby range of large varmint calibres.
Large game; Bolt action, Take your pick of anything over 27 cal. Preferably over 30 cal


*Bird hunting.

12GA shotgun. Pump, semi-auto, over and under.

*Scrub gun for medium game.

Short barrel lever, pump action shotgun or rifle. Winchester 'trapper' 44/40, 30/30. BLR 308.

*Fun gun.

Cheap shooting rifle for shooting tin cans, targets etc.
Lever action, pump or semi-auto .22.

So I think one could get away with just having 10 rifles and a shotgun or 2. But as its a hobby, interest in a new style of rifle or new calibre will always motivate us to get a new toy..