This is a very interesting match-up. I am very happy Manny didn't just wait for the outcome of Mayweather Marquez. With that being said I couldn't say who would win but I would give Cotto the edge. Natural weight and a viscious body puncher when he does go down there anymore. Pacquaio would probably just have to box and pick his shots and then later maybe if Cotto is hurt at all go after him in the championship rounds.