If you mean could he have done anything differently on Saturday to win, almost certainly not... Of course he can punch and so that slim chance was always there, but since Manny could stand up to his power and saw everything coming, slim may have left town after the first couple of rounds. If your asking could he have won if he were a couple years younger and never lost to Margarito, I have no idea how much more likely it would've been, I guess at least significantly... Thing is that people assert the loss to Margo ruined his confidence, but it was sort of that same bravado that got him in huge trouble against fighters he should've beaten in Corley and Torres. I think Cotto was always going to get lured into a brawl with Manny one way or another, and that's not a fight he would have ever won.