Of course Mayweather can beat Manny and vice versa.

Mayweather

1. Great Defense
2. Great Offense
3. Very Good Power
4. Great Speed
5. Great Stamina
6. Good punch output
7. Great Counterpuncher
8. Very Good Combinations
9. Backs up weaker fighters or fighters that have expended their energy (Judah). Check his Baldomir and Oscar fight to see what happens against stronger opponents.
10. Great Chin (it rarely been tested but it's held up great)
11. Genius Boxer

Pacquiao

1. Very Good Defense (I'm talking about the constantly improving Pac, please don't bring up Marquez. He's has improved vastly since those fights)
2. Great Offense
3. Great Power
4. Great Speed
5. Great Stamina
6. Great Punch output
7. Great Puncher with both hands
8. Great Combinations
9. Backs up weaker and "stronger" opponents
10. Great chin
11. Genius corner and brilliant execution by Pac.


It's pretty damn even from how I see it but I have to go with Pacquiao by unanimous decision.

Mayweather moves very effectively against stronger opponents and he could outpoint Pac. Pacquiao is the stronger man in this one and I believe his superior combinations will be the difference. I expect/hope the fight to be much more competitive than Cotto. It's not a bandwagon thing either. The only times I didn't pick Pac was against supposedly stronger opponents (DLH and Cotto). He's proven me wrong twice, and against Mayweather I feel the size difference is way less of an issue then Cotto and DLH.

Good luck to both fighters. Both are living legends in my opinion.